SeerPharma Pty Ltd :: DISCover web-based training :: SNPs: Identification and Uses

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SNPs: Identification and Uses

Description: The SNPs course covers the methods used to identify and detect SNPs, and the uses of SNPs as markers for disease association and other genome-wide screening approaches.

COURSE OUTLINE INTRODUCTION
1. Course Information
2. Interface Tour
3. Course Overview

DNA VARIATIONS
4. Objectives
5. Introduction
6. Describing Variation
7. Types of Polymorphism
8. Marker Heterozygosity
9. Progress Check

SNPs
10. Objectives
11. Origin of SNPs
12. Classes of SNPs
13. Progress Check

SNP DETECTION
14. Objectives
15. Overview of Approaches
16. Targeted SNP Discovery
17. Random SNP Discovery
18. Progress Check

DATABASES
19. Objectives
20. TSC
21. HGBase
22. dbSNP
23. Progress Check

STUDY DESIGN
24. Objectives
25. Considerations
26. Measuring Variation
27. Regional Rates
28. Power of Detection
29. Progress Check

USES
30. Objectives
31. Whole Genome LD
32. Candidate Gene Association Studies
33. Progress Check

GENOTYPING
34. Objectives
35. Technology Requirements
36. Methods
37. Progress Check

CONCLUSION
38. Summary

COURSE OBJECTIVES

Students completing this course should be able to:

List the three common types of polymorphisms
Define what a SNP is and how it originates
Describe the three types of methods used to identify and detect SNPs
Specify the resources that are available for SNP analyses
Calculate the normalized rates of SNP occurrence
List two examples of SNP genotyping methods
Define the requirements of genotyping assays
Explain the use of SNPs as genetic markers
Describe the use of SNPs for association studies.

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