SeerPharma Pty Ltd :: DISCover web-based training

HIV and AIDS: Treatment

Description: The human immunodeficiency virus, or HIV, is the virus that causes Acquired Immune Deficiency Syndrome (AIDS). HIV is a retrovirus, and is composed of a central core made of proteins and RNA, surrounded by an "envelope" or membrane made of other proteins and fatty acids. This course presents basic scientific and medical background information about disease progression and treatment options, including prognosis, pharmacological therapies and emerging therapies.

COURSE OUTLINE

INTRODUCTION
1. Course Information
2. Interface Tour
3. Course Overview

PROGNOSIS
4. Objectives
5. Prognosis
6. Disease Progression in Children
7. Host-Disease Interactions
8. Progress Check

PHARMACOLOGICAL THERAPIES
9. Objectives
10. NRTI and NtRTI
11. NNRTI
12. Protease Inhibitors
13. Entry/Fusion Inhibitors
14. Progress Check

EMERGING THERAPIES
15. Objectives
16. Gene Therapy
17. RNAi
18. Biological Agents
19. Nuclear Translocation Inhibitors
20. Integrase Inhibitors and Zinc Fingers
21. Vaccine
22. Progress Check

TREATMENT STRATEGIES
23. Objectives
24. Drug Therapy Outcomes
25. Initiating Therapy
26. Combination Therapies
27. Factors Affecting Outcome
28. Effects of Drug Therapy
29. Lipodystrophy
30. Drug Interactions
31. Concomitant Diseases
32. Adverse Events
33. Therapeutic Approach
34. Patient Adherence
35. Progress Check

CONCLUSION
36. Summary

COURSE OBJECTIVES

Students completing this course should be able to:

List the factors that lead to a poor prognosis
Explain how host polymorphisms delay or speed the development of HIV
Describe the mechanism of action for NRTIs, NNRTIs, PIs, and fusion inhibitors
Describe the emerging treatment options in HIV therapy
Identify potential uses of each treatment
List the components of common drug regimens
Explain the considerations that apply to concomitant medications
List common adverse events
Describe how treatment regimens can be affected by patient adherence

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