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HIV and AIDS: Cause

Description: The human immunodeficiency virus, or HIV, is the virus that causes Acquired Immune Deficiency Syndrome (AIDS). HIV is a retrovirus, and is composed of a central core made of proteins and RNA, surrounded by an "envelope" or membrane made of other proteins and fatty acids. This course presents basic scientific and medical background information about HIV infection, including pathophysiology and epidemiology.

COURSE OUTLINE

INTRODUCTION
1. Course Information
2. Interface Tour
3. Course Overview

PATHOPHYSIOLOGY
4. Objectives
5. Structure of HIV
6. HIV Polymorphism
7. Polymorphic Strain Classification
8. Transmission and Infection
9. Cellular Consequences
10. HIV Target Cells
11. T Cells, B Cells, and APCs
12. Immune Activation
13. HIV Evasion of the Immune Response
14. Progress Check

EPIDEMIOLOGY
15. Objectives
16. Incidence and Prevalence
17. Gender and Prevalence
18. Developing Countries: West Africa
19. Eastern and Sub-Saharan Africa
20. South-East Asia
21. High-Income Countries
22. Progress Check

CONCLUSION
23. Summary

COURSE OBJECTIVES

Students completing this course should be able to:

Describe the structure of HIV
Discuss how HIV polymorphism makes the virus a difficult target for vaccines or traditional medicines
Explain the process by which an HIV infects a human cell
Describe the effects of HIV on the human immune system
List the incidence and prevalence rate of HIV in various countries worldwide
Explain why the age and gender status of new HIV cases is causing an increase in the rate of childhood HIV infection
Describe the economic and social issues that affect HIV/AIDS treatment in the developing world

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