SeerPharma Pty Ltd :: DISCover web-based training

Heart Failure: Cause

Description: More than one in four Americans has some type of cardiovascular disease that can eventually lead to heart failure (HF), the inability of the heart to pump a sufficient amount of blood into the blood vessels. Many of these diseases have common risk factors and an interrelated pathogenesis. Despite recent therapeutic advances, heart failure is the only major cardiovascular disorder that is increasing in incidence and prevalence.

COURSE OUTLINE

INTRODUCTION
1. Course Information
2. Interface Tour
3. Course Overview

EPIDEMIOLOGY
4. Objectives
5. Incidence and Prevalence
6. Morbidity and Mortality
7. Economic Impact
8. Progress Check

PATHOPHYSIOLOGY
9. Objectives
10. Acute vs. Chronic Heart Failure
11. Left-sided vs. Right-sided Heart Failure
12. Systolic vs. Diastolic Heart Failure
13. The Frank-Starling Mechanism
14. RAAS Activation
15. Effects of RAAS Activation
16. Autonomic Response
17. Adaptive Cardiac Mechanisms
18. Underlying Conditions
19. Progress Check

CONCLUSION
20. Summary

COURSE OBJECTIVES

Students completing this course should be able to:

Describe the epidemiology of heart failure
Identify the morbidity and mortality associated with heart failure
Describe the economic impact of heart failure
Describe the definition, types, and causes of heart failure
Describe the Frank-Starling Mechanism and how it affects preload and cardiac output
Describe the role of the sympathetic nervous system in heart failure
Describe how chronic sympathetic stimulation contributes to structural and hemodynamic abnormalities in heart failure

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