SeerPharma Pty Ltd :: DISCover web-based training

Dyslipidemia: Cause

Description: Dyslipidemia is a disorder of the amount of lipids in the blood, and is a primary risk factor for the development of atherosclerosis and subsequent cardiovascular diseases. Therefore, understanding and treating dyslipidemia is a key step in preventing life-threatening events such as stroke and myocardial infarction. This course introduces the types of lipids and their metabolic pathways, which play an important role in cardiovascular disease.

COURSE OUTLINE

INTRODUCTION
1. Course Information
2. Interface Tour
3. Course Overview

PATHOPHYSIOLOGY
4. Objectives
5. Simple Lipids
6. Complex Lipids
7. Lipoproteins
8. Cholesterol Biosynthesis
9. Exogenous Pathway
10. Endogenous Pathway
11. Reverse Cholesterol Transport
12. Description of Dyslipidemias
13. Progress Check

EPIDEMIOLOGY
14. Objectives
15. Age of Onset
16. Cardiovascular Disease Types
17. Prevalence and Mortality
18. Costs
19. Risk Factors
20. Human Studies and Trials
21. Progress Check

CONCLUSION
22. Summary

COURSE OBJECTIVES

Students completing this course should be able to:

Understand the different types of lipids, lipoproteins, apolipoproteins and triglycerides, and how they contribute to cardiovascular disease
Describe key features of cholesterol biosynthesis
Identify the six types of lipoproteins
Describe the roles of the different lipoprotein types in lipid transport
Describe the important pathways in lipid and lipoprotein metabolism
Define dyslipidemia and describe how dyslipidemias are commonly classified
Describe known links between lipoproteins and atherosclerosis
Describe ways in which LDL reduction and HDL increase may produce clinical benefits
Identify the key findings of trials that have examined the correlation between lipid levels and CHD
Identify important findings from both primary and secondary prevention trials with lipid-lowering drugs

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