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Bipolar Disorder: Treatment

Description: An incurable mental illness, bipolar disorder (previously called manic-depression) produces episodes of major depression alternating with episodes of mania in its sufferers. Patients experience alterations in mood, behavior, and cognition. Moreover, other aspects of brain functioning such as sensory perception, appetite, or sleep-wake cycle regulation are altered. In this course, you will be introduced to the treatment options available to patients with bipolar disorder.

COURSE OUTLINE

INTRODUCTION
1. Course Information
2. Interface Tour
3. Course Overview

MOOD STABILIZERS
4. Objectives
5. Lithium
6. Valproate
7. Progress Check

ANTIPSYCHOTICS
8. Objectives
9. Olanzapine
10. Risperidone
11. Quetiapine
12. Ziprasidone and Aripiprazole
13. Progress Check

ANTICONVUSANTS
14. Objectives
15. Carbamazepine
16. Lamotrigine
17. Topiramate and Other Agents
18. Progress Check

NON-PHARMACOLOGICAL
19. Objectives
20. Electroconvulsive Therapy (ECT)
21. Psychosocial Therapy
22. Progress Check

TREATMENT PRACTICE GUIDELINES
23. Objectives
24. Acute Treatment
25. Maintenance Treatment
26. Progress Check

PROGNOSIS AND COMORBIDITY
27. Objectives
28. Natural Course and Clinical Outcome
29. Substance Abuse
30. Anxiety and Personality Disorders
31. Progress Check

CONCLUSION
32. Summary

COURSE OBJECTIVES

Students completing this course should be able to:

For the common pharmacological agents lithium and valproate, explain the major pharmacological features and proposed mechanisms of action
For lithium and valproate, identify how these agents affect the brain and how these changes benefit the patient
For lithium and valproate, describe any known side effects
Explain the pharmacology and proposed or known mechanisms of action of the antipsychotics used for treatment of bipolar patients
List the indications, advantages, and side effects of each antipsychotic presented
Explain the pharmacology and proposed mechanism of action for each agent presented in this section
List the beneficial effects and side effects of each agent presented in this section
Discuss the indications, advantages, and proposed mechanism of action for electroconvulsive therapy (ECT)
Explain what psychosocial therapy is and how it is applied to patients with bipolar disorder
Discuss the guidelines for psychiatric treatment of bipolar disorder as set by the APA
Enumerate the recommendations for acute treatment of manic or mixed episodes, depressive episodes, and rapid cycling
Summarize the recommendations for pharmacologic and psychosocial intervention for the maintenance phase of bipolar disorder
Discuss the natural course and clinical outcomes of bipolar illness
List the concomitant diseases and conditions of bipolar disorder
Discuss the high prevalence of suicide in bipolar patients

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