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Acid-related Disorders: Cause
Description: Acid-related digestive disorders are a burden on patients, physicians, and society because they are highly prevalent, have varied signs and symptoms, and are costly. This course covers the pathophysiology and epidemiology for acid-related diseases, including gastroesophageal reflux disease, or GERD, peptic ulcer disease, and hypersecretory syndromes.
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COURSE OUTLINE
INTRODUCTION
1. Course Information
2. Interface Tour
3. Course Overview
SYSTEM OVERVIEW
4. Objectives
5. The Esophagus
6. The Stomach
7. The Mucosa
8. Parietal Cell Physiology
9. Gastric Acid Secretion Rate
10. Secretion Stimulation: Cephalic Phase
11. Secretion Stimulation: Gastric Phase
12. Secretion Stimulation: Intestinal Phase
13. Progress Check
PATHOPHYSIOLOGY
14. Objectives
15. Gastroesophageal Reflux
16. GERD
17. GERD and Pulmonary Disease
18. GERD and ENT Disease
19. Peptic Ulcer Disease
20. Other Acid-related Disorders
21. Progress Check
EPIDEMIOLOGY
22. Objectives
23. Epidemiology of GERD
24. Epidemiology of Peptic Ulcer Disease
25. Progress Check
CONCLUSION
26. Summary
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COURSE OBJECTIVES
Students completing this course should be able
to:
- Review the normal physiology of the esophagus and the stomach
- Explain the origin of acid-related disease
- Identify the four types of secretory cells
- Describe the spectrum of GERD and define NERD and ENRD
- Identify the triggers of GERD and their role in disease exacerbation
- Describe how acid-related disorders can lead to problems in other systems such as the lungs, ears, nose and throat
- Explain the origin of peptic ulcer disease and other acid-related disorders
- Describe the prevalence of GERD
- Discuss the epidemiology of peptic ulcer disease
- Understand the role of specific risk factors in the development of peptic ulcers
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